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Showing posts from December, 2020

Melatonin — A Promising Candidate for Prevention and Treatment of COVID-19

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Figure 1.   I-MASK+ (Prophylaxis & Early Outpatient Treatment Protocol for Covid-19) In Figure 1, it shows the  prophylaxis protocol  proposed by FLCCC Alliance. [1]  And, the below items on the proposed list: Vitamin D3 Vitamin C Quercetin Zinc Melatonin are added as immune boosters for fighting Covid-19 virus. In this article, we will discuss what melatonin is. Melatonin — A promising treatment option for COVID-19 Melatonin , a hormone secreted by the pineal gland that regulates the sleep-wake cycle and is commonly used as an over-the-counter sleep aid.  It has wide-ranging effects as an antioxidant, anti-inflammatory, and immunomodulatory compound. Based on multiple studies, melatonin is believed to be a promising candidate for prevention and treatment of Covid-19: University of Toronto [2] Based on scientists' review, they discuss evidence implying that  melatonin Prevents SARS-of CoV-2 infection Is suitable as an effective anti-infl...

Top Zinc-Rich Foods for Better Immunity

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Zinc plays an essential role in supporting immune function, helping the body fight infections, heal wounds, and maintain normal cellular processes. According to the NIH, adults should aim for 8 mg per day for women and 11 mg per day for men , with an u pper limit of 40 mg per day to avoid interfering with copper and iron absorption. [1]  Most people can meet their needs through food alone, and zinc toxicity from diet is extremely rare . [8] Why Zinc Matters Zinc is found throughout the body and is required for: Immune defense against bacteria and viruses DNA and protein synthesis Growth and development during pregnancy, infancy, and childhood A balanced diet is usually sufficient. Supplements are generally recommended only when a deficiency is confirmed by a healthcare professional. Best Foods for Zinc Zinc is found in cells throughout the body. It helps the immune system fight off invading bacteria and viruses. The body also needs zinc to make proteins and DNA , the genetic ...

Immunosenescence — Weaker Immune System of the Elderly Explained

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Figure 1.   Diversity and clonal selection in the human T-cell receptor repertoire [1]   Key Points 1. T-Cell Receptor Diversity: As we age, T-cell receptor diversity declines due to shrinking thymus function. Thymus involution (thymus shrinkage) leads to fewer new T cells. 2. Immunosenescence: Immunosenescence refers to the age-related weakening of the immune system. It includes: Accumulation of dysfunctional memory T cells. Shortened telomeres (reduced cell lifespan). Impaired immune regulation. 3. Overall Changes: Aging results in: Weaker immune responses to new infections and vaccines. A shift toward inflammation. Increased susceptibility to autoimmune diseases, cancers, infections, and other age-related conditions. 4. Potential Solutions: Biomarkers (like CXCL9) can help identify individuals at risk for immunosenescence. Dietary interventions (such as prolonged fasting cycles) may alleviate immunosenescence. 5. COVID-19 and Aging: Older individuals are more...

Ivermectin & Carrageenan Study Shows Positive Results Targeting COVID-19

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Figure 1.  I-MASK+ (Prophylaxis & Early Outpatient Treatment Protocol for Covid-19) Headline News FDA Drops Ivermectin Bombshell   (08/11/2023) Doctors are free to prescribe ivermectin to treat COVID-19, a lawyer representing the U.S. Food and Drug Administration (FDA) said this week.  Top Yale Doctor/Researcher: ‘Ivermectin works,’ including for long-haul COVID Oxford University explores anti-parasitic drug ivermectin as COVID-19 treatment  (06/23/2021) In an open-label randomized clinical trial of high-risk patients with COVID-19 in Malaysia, a 5-day course of oral ivermectin administered during the first week of illness did not reduce the risk of developing severe disease compared with standard of care alone . (02/18/2022) Based in the southern end of Greater Buenos Aires, Argentina, Eurnekian Public Hospital recently sponsored a clinical trial targeting COVID-19 called the IVERCAR study. [2] The sponsor was joined by other local hospitals ac...

Hesperidin — a promising adjuvant treatment option against SARS-CoV-2 infection

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Hesperidin is a bioflavonoid , a type of plant pigment with antioxidant and anti-inflammatory effects found primarily in citrus fruit  (see Figure 1).  Oranges, grapefruit, lemon, and tangerines all contain hesperidin, which is also available in supplement form. Note that  hesperidin is present in highest concentration in the peel . Figure 1.  Citrus fruits A Traditional Herbal Medicine Hesperidin is a classical herbal medicine used worldwide for a long time with an excellent safety profile . The safety of hesperidin was confirmed by FASEB (Federation of American Societies of Experimental Biology) upon request of the FDA. Cellular Entry of Covid-19 Cell entry of Covid-19 depends on two consecutive steps: Binding of the viral spike (S-protein) to host cellular receptors  Followed by priming of S-protein by cell proteases Recently, researchers showed that COVID-19 uses the ACE-2 receptor for entry and the serine protease TMPRSS2 for priming of S-protein. [4...