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Showing posts with the label Melatonin

Melatonin Controlling the Balance between Th17 & Treg Cells

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Disclaimer: This article is for informational purposes only and does not constitute medical advice. Melatonin’s role in immunomodulation remains under investigation; its use for autoimmune or inflammatory disorders should be undertaken only under specialist supervision. Both Treg dysfunction and hyperactive responder T-cell proliferation contribute to disease. In this article, we will discuss the importance of regulating between Th17 and Treg cells. F igure 1.    IL‐6   mediates Th17 / Treg balance. IL‐6 induces Th17 differentiation from naïve T cells together with TGF‐β . On the other hand, IL‐6 inhibits Treg differentiation induced by TGF‐β . IL-6: Regulator of Treg/Th17 Balance Inflammatory T cells are thought to be central to the pathology of autoimmune diseases . Especially, the recently identified T‐cell subset, the  Th17  cells, shows pro‐inflammatory functions and plays a critical role in various autoimmune disorders. Recent studies have de...

Melatonin — A Promising Candidate for Prevention and Treatment of COVID-19

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Figure 1.   I-MASK+ (Prophylaxis & Early Outpatient Treatment Protocol for Covid-19) In Figure 1, it shows the  prophylaxis protocol  proposed by FLCCC Alliance. [1]  And, the below items on the proposed list: Vitamin D3 Vitamin C Quercetin Zinc Melatonin are added as immune boosters for fighting Covid-19 virus. In this article, we will discuss what melatonin is. Melatonin — A promising treatment option for COVID-19 Melatonin , a hormone secreted by the pineal gland that regulates the sleep-wake cycle and is commonly used as an over-the-counter sleep aid.  It has wide-ranging effects as an antioxidant, anti-inflammatory, and immunomodulatory compound. Based on multiple studies, melatonin is believed to be a promising candidate for prevention and treatment of Covid-19: University of Toronto [2] Based on scientists' review, they discuss evidence implying that  melatonin Prevents SARS-of CoV-2 infection Is suitable as an effective anti-infl...