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Showing posts with the label sarcopenia

Protein & Longevity: How the Science Has Shifted (2017 → 2026)

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Figure 1.  Based on a survey of over 1500 people of 65 and over in the UK (source: @SilverM00NSHOTS) Figure 2.  Rockwood frailty index [61] For years, longevity discussions emphasized restricting protein to avoid overstimulating IGF‑1 and the mTOR pathway. Early frameworks—such as the 2017 Mitochondrial Metabolic Therapy diet—recommended 45–55 g/day to minimize nitrogen load, reduce IGF‑1, and limit mTOR activation. These concerns were grounded in real physiology: excess protein can increase nitrogen waste, elevate IGF‑1, and activate growth pathways linked to cancer risk. [17,47] But as the population ages and long‑term data accumulate, the scientific lens has widened. By 2026, the consensus has shifted: for older adults, the more urgent and measurable threat is muscle loss—not moderate protein intake. The 2026 Update: A Higher Baseline for Healthy Aging Recent clinical guidelines now recommend 1.0–1.2 g/kg of body weight for most healthy older adults. For those ...

Protein Prescription for Aging Muscles: Why Leucine Matters More After 60

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The Muscle-Building Supplements That ACTUALLY Work (YouTube link ) Muscle and bone health aren’t just parallel concerns—they’re mutually reinforcing systems. Protecting one helps preserve the other. That’s why interventions like resistance training, adequate protein (especially leucine), vitamin D, and mobility-focused exercise are central to healthy aging strategies. Leucine: A Key to Combating Age-Related Muscle Loss  Maintaining muscle mass is difficult as we age due to anabolic resistance , a reduced ability of aging muscle to respond to protein and exercise (Breen & Phillips, 2011). This resistance is a major factor in sarcopenia ( age-related muscle loss ). To counter this, older adults need a higher protein intake ( 1.2–2.0 g/kg of body weight/day , compared to 0.8 g/kg for younger adults) and should aim for 25–40 grams of high-quality protein per meal (Deutz et al., 2014; Moore et al., 2015). Leucine , a branched-chain amino acid, is the primary trigger for muscle pr...